Yes there are weak points (the huge one with Signal being: requiring your cell phone number as a part of authentication) but that's far beyond the level of technical expertise required to, say, just intercept clear text communications, ex from Telegram. If a government is wiretapping you then you've got problems that neither Signal nor Telegram can solve.
Now maybe you will suspect that a three letter agency will force them to do something bad, like send a suspect a hacked/backdoored version of the app or something but by and large i don't think they would do that. They'd just go to Google or Apple and put a keylogger on your phone, or some other solution. Realistically, though, this is a level of effort far beyond what >99% of all humans need to worry about. Choosing Telegram over Signal because you're afraid the government is manipulating your Signal app is a sign of incoherent paranoia.
A more serious concern would be, for example, the government capturing all data sent across the Internet and then holding onto it until some hypothetical future computer is developed that can just break the encryption. That's still pretty silly but it's something the US (at least) is doing. Still way beyond what they would need to get your Telegram messages because, again, they don't need to decrypt those. They can just look.
The difference being: Signal cooperates as they're legally required to buy do not have the technological capability to betray you. Telegram has the technological capability to betray you (and governments can spy on Telegram, with or without Telegram's assistance) but refuses to cooperate.
Heinlein's "all you zombies" is an early version of this.
In terms of biology, it's extremely rare for humans to have fully functioning sets of both reproductive systems. The reproductive physiology develops from the same parts so it either develops "male", "female", or (more common than people think) somewhere in between but not "both". A clone may or may not even develop in the same way.
One other possibility, though also very rare. is near-identical twins. If twins have the same genetics (in other words, they're identical twins) but have intersex conditions that result in different reproductive development it's conceivable that they could reproduce with each other. It's uncommon to be fertile incongruous with your genetics, though, so again: this would be extremely unlikely.
That said, in a sci-fi context there are some options. Biological hermaphroditism is possible in animals, though there aren't any vertebrates on Earth, so conceivably an alien species could encounter this problem.
Advanced medicine could also build people a new reproductive system and implant it, giving them the counterpart they lacked.
Of course, in that case, advanced medicine may also be able to give you someone else's reproductive genetics (ex, implanted sperm or eggs) and thus effectively sidestep the genetic problems. I'm imagining a particularly narcissistic person getting a gender-flipped clone of themself and using someone else's genetic material to have a kid with themself but also avoid the shallow gene pool problem.
Of course, you don't need to go that far. If you're female (or have those parts anyway) you can just do IVF. Don't even need to clone yourself, then.
As well as the package manager (and release type/schedule as mentioned in a different reply) you might want to look at the overall structure.
Does the distro use selinux or app armor (you probably want at least one)? Does it follow traditional distro structure like Ubuntu/Debian or is it weird like atomic (ex Silverblue) or declarative (ex Nixos) distro? Is it a minimalist distro (Arch is the big modern one) it maximalist (Suse)? Those kinds of things can also be informative.
One of the key features of authoritarian follower personalities is that they're desperate to be normal. Like, they're terrified of the idea that they're not just like everyone else despite the fact that they are big weirdos. People who are afraid of being weird, or who get weirdly judgemental about weirdness, is a big red flag for me, personally.
They can order Signal to turn over data (and the have) and signal has complied when it was legally required of them to do so, handing over all of their no data.
That's the difference.
If that weren't true they wouldn't be so constantly upset about E2EE.
Specifically, they have the technological ability to prevent some crimes on their platform and have repeatedly refused to do so, or even engage with attempts to do so. Because they're not E2EE they can see what everyone is doing and are therefore legally required to step in when someone is (for example) selling drugs on their platform.
Signal (etc) have no insight into the actions of their users and when they are legally required to take action they do, they take the minimal legally required action (unlike other services from, ex, Apple). Signal follows the law, Telegram does not.
States are really pissy about E2EE for this (and other) reasons. They want to get rid of it because they want to monitor all private conversations. That's why E2EE is important.
I get it, i don't want to live in China but i don't want to live in whatever Elon Musk has planned for the US, either, and his wealth gives him undue influence over... pretty much everything. You're not convincing me you've got a consistent take here if you're cool with Twitter but not TikTok.
In that sense, TikTok is really their competition. They're upset not because it steals your data, they're upset because they're not the ones getting your data.
Europe does have some Union representation in the corporate org structure, fwiw. How much that helps... well... i'm not sure, i haven't seen it up close.
Fake speeding tickets as a service...