jocanib @ jocanib @lemmy.world

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214

Joined

2 yr. ago

The paper isn't paywalled:

Purported direct mechanisms to explain the association between new-onset diabetes and prior SARS-CoV-2 infection include evidence that the SARS-CoV-2 entry receptor ACE2 is expressed on insulin-producing β cells, SARS-CoV-2 infection contributes to dysregulation of glucose metabolism, and individuals who have an increased susceptibility to diabetes are especially vulnerable following SARS-CoV-2 infection because dysregulated glucose metabolism and direct viral damage to β cells impairs their compensatory mechanisms, leading to β-cell exhaustion. 7 However, there is no clear underlying mechanism explaining the association between SARS-CoV-2 infection and subsequent increased risk of incident diabetes. 7,8 While there are reports of an association between SARS-CoV-2 infection and subsequent increased risk of incident type 1 diabetes in children using routinely collected health record data, 5,6,67 there are concerns about the validity of such studies because the data sets used did not capture asymptomatic SARS-CoV-2 infections in children. Population-based studies that reported an increased incidence rate of type 1 diabetes in children and adolescents during the pandemic did not find an increase in the frequency of autoantibody-negative type 1 diabetes 12,23,68 ; this suggests that the increase in incidence may be due to an immune-mediated mechanism.

Proposed indirect effects of the COVID-19 pandemic and containment measures that may be associated with diabetes incidence include changes in lifestyle, change in the pattern of pediatric non–COVID-19 infections, and increased stress and social isolation. 12,69-71 It has been proposed that frequent respiratory or enteric infections in children are potential triggers for islet autoimmunity, promote progression to overt type 1 diabetes, or are precipitating stressors. 72 Pandemic containment measures were associated with a decrease in viral respiratory and gastrointestinal tract infections among children. 69 Given this finding, the observed increased incidence rate of type 1 diabetes during the pandemic is contrary to what would be expected based on the decrease in viral infections among children during the pandemic.

There may have initially been a catch-up effect caused by lower incidence rates of pediatric diabetes early in the pandemic, possibly due to delays in diagnoses associated with hesitancy to seek care or barriers to access care.12-14 However, the reported incidence of diabetes remained increased in studies that included data from beyond the first year of the pandemic. 23,32,49,52,53,58-60,63 Furthermore, there appears to have been a disruption to the historic seasonal pattern of autoantibody-positive diabetes incidence in children. 23,24 The reasons for this remain uncertain but may be related to the effects of COVID-19 containment strategies, such as lockdowns, both at the beginning of the pandemic and at subsequent times in different countries. 73

The issue really is about double-standards. People call Israel “apartheid” for refusing to give people in the occupied territories citizenship status. But I didn’t hear any Americans calling the United States apartheid when we occupied Iraq, and didn’t give Iraqis US citizenship.

This is flat out ridiculous. Politics by keyword does not cut it. I'm not going to defend the US invasion or occupation of Iraq but the US wasn't controlling the territory in order to one day make it the 51st state, by moving Americans there en masse while demolishing the homes, crops and livelihoods of Iraqis.

The much closer analogy is the British occupation of Northern Ireland; territory it claimed as its own (the full country name is the United Kingdom of Great Britain and Northern Ireland). The people of Northern Ireland did have British citizenship, whether they wanted it or not.

If you genuinely think your analogy is a good one, please, read some history and think a bit harder. You don't have to defend the indefensible.

This lil robot was trained to know facts and communicate via natural language.

Oh stop it. It does not know what a fact is. It does not understand the question you ask it nor the answer it gives you. It's a very expensive magic 8ball. It's worse at maths than a 1980s calculator because it does not know what maths is let alone how to do it, not because it's somehow emulating how bad the average person is at maths. Get a grip.

How did it backfire? It's working exactly as intended, surely? Workers trapped by employee healthcare, huge businesses put at a substantial advantage relative to small businesses, and trillions of dollars flowing to idle shareholders in return for doing nothing useful.

No it isn't. But you know that.

When you want to switch you’re essentially saying “I’m not showing up to my shift”

Do you understand what a "switch" is?

Overtime in the hospitality trade?

Where?

Of course it’s legal. Why wouldn’t it be?

I'm assuming you're USian?

The question almost anywhere else in the wealthy world is why would it be legal? The manager does not need to know therefore the manager has no right to ask.

How Target Knew a High School Girl Was Pregnant Before Her Parents Did

Facebook turned over chat messages between mother and daughter now charged over abortion

Unsolved cases don't typically get closed. And when they eventually get solved, it hits the news. You've read many stories like it, for sure.

In this case, it sounds like there is new evidence. No big mystery.

I got to do that once, being in a country where we get 5 weeks paid holiday every year. I hadn't taken any in a year and the boss tried to take the piss so I explained that I wouldn't be working my notice and left.

That was back in the day when jobs were easy to come by. So I got eight weeks pay the following month.

Company disappeared off the internet three months later.

Well, OK. But they didn't have a point that needed explaining. They're not being sincere and there's no need to give them an assist, especially if you're going to leave it to me to explain why your generous interpretation of their 'point' is bullshit.

I'm British. The slave trade is but one of our many world-fucking sins.

There are people alive today whose grandparents were born into slavery. Given that slavery did not actually end with the civil war, and Jim Crow, and mass incarceration, and the current dismantling of civil rights era laws, there are hundreds of millions of people alive today who are still directly suffering the aftermath.

So no, it is nowhere out of living memory and I am astonished that there are two people in one place so ignorant that they are willing to argue that it is.

No. And you can clearly read well enough to know perfectly well that is not what I am saying. Pretending to be obtuse is such a bizarre tactic, why do you do it?

You're going to have to explain how you think I'm drawing a line there.

I didn't draw any lines. Your English is easily good enough to comprehend what I wrote. If you misunderstood, read it again. If you're being deliberately obtuse, fuck off.

I'm not USian either.

There is no sense in allowing a private profit from a natural monopoly with no risk attached (we're never going to decide we can live without clean water and water is supplied geographically, you don't get to choose the provider). Demand will always be there and, as a society, we are much better off doing all the work you describe at cost. Lining the pockets of shareholders does not make any sense. But that is exactly what is happening.

I'm in the UK. It is an extremely sore point here: Water firms’ debts since privatisation hit £54bn as Ofwat refuses to impose limits

Ofwat is refusing to limit the soaring debts run up by water companies as research reveals the firms have outstanding borrowing of almost £54bn accrued since privatisation.

Customers are paying on average £80 or 20% of their water bill towards servicing debt and rewarding shareholders, according to the Competition and Markets Authority (CMA).

The scale of debt, or gearing, taken on by the nine main water and sewerage companies in England is raising concerns about their financial stability as interest rates rise.

The level of net debt held by water companies is revealed as Guardian data shows the main water and sewerage firms in England have paid dividends to shareholders of £65.9bn up to 2022.

Note the £54bn in debt they're charging us 20% to cover (first para) compared to the £65.9bn they've doled out to idle shareholders (last para), mostly via tax havens, just to add insult to injury.

And the sewage they are spilling into our waterways because they have not invested in infrastructure. Why would they when they can hand the money to shareholders and rely on the govt not to make them meet even the most minimal of standards?

People are not stupid. There are overwhelming majorities in the UK for nationalising water (and rail, mail, energy, all the stuff that it makes no sense to privatise). But democracy does not mean shit when there's profit to be extracted. And the profiteers do their very best to make us stupid by insisting there is no other way and wearing everyone down until they believe it. Which is easy, because they own all the media so even if we don't entirely buy their bullshit, it's very hard to hear anything else above the din they're making.

Apart from the fact that you're pretending 150 years (with the civil rights legacy still not resolved) is much the same as a whole millennium, you're also ignoring the substantial differences between the slavery your ancestors endured and the chattel slavery practiced as a result of the transatlantic slave trade.

Chattel slavery meant a lifetime of slavery and children born into slavery, often through rape-for-profit by slaveholders. Enslaved families being ripped apart on a whim if a sale was convenient for their enslaver.

The transatlantic element meant enslaved people were permanently recognisable as slaves.

And the creation of the particular form of racism found in the Americas to prevent poor whites from fraternising with their most natural allies.

This is a terrific read, if you want to educate yourself: I know why poor whites chant Trump, Trump, Trump

An investment in African slaves also ensured a cost-effective, long-term workforce. Female slaves were often raped by their white owners or forced to breed with male slaves, and children born into slavery remained slaves for life. In contrast, white female servants who became pregnant were often punished with extended contracts, because a pregnancy meant months of lost work time. From a business perspective, a white baby was a liability, but African children were permanent assets.

As the number of African slaves grew, landowners realized they had a problem on their hands. Slave owners saw white servants living, working, socializing, and even having babies with African slaves. Sometimes they tried to escape together. What’s more, freed white servants who received land as part of their freedom dues had begun to complain about its poor quality. This created a potentially explosive situation for landowners, as oppressed workers quickly outnumbered the upper classes. What was to prevent freed whites, indentured servants, and African slaves from joining forces against the tyranny of their masters?

Yeah, that's not how it works. If it was, there would be no privatised water companies because we're not all fucking daft. But we are ruled by kleptocrats so, you know. IMF Forces Water Privatization on Poor Countries