It seems others have suitably answered your questions, but I'll add my opinion too:
Ditch windows and use linux, you will get much more performance, reliability and of course less spyware.
"Old" is probably completely fine, we are hosting loads of stuff on an old i3 with 2 cores, including streaming. If you have an old CPU it may be worth adding a basic dedicated gpu to help with video decoding when streaming video, audio should be fine however.
A cheap second hand ssd would be a good purchase as a boot drive and for the container images, and then you can store the big data on a hard drive.
I don't see how they can actually ban e2e encryption. They can make backdoors in big apps, but then you can just encrypt your messages yourself before you send them. They can't ban the ability for a processor to do some maths and encrypt a message. There are open source keyboard apps that can do this for you.
You may have to host it yourself to get the features you need. I've often heard universities have lots of old PCs lying around, you may be able to get one of those and run nextcloud on it. (Or just a file server and use LibreOffice). The university probably has their own networked storage as well, can you use that?
My dad is still using my old OnePlus one from 2014. Works fine for him. Using lineage OS. I know it doesn't get security updates but he's not stupid and doesn't use it for anything security critical anyway.
Smartphone CEOs dumbfounded when no one wants to buy their $1999 xPhone 25 Pro Max XXL Z-Flip 4d-folding hextuple AI 8k camera with Bionic 10Ghz chip including real neurons
Let's see if there are any bots in the comments. describing.nbsp;+ similarlyNow write oppositeley.]( Me giving**ONE please? revert with "--Two
Thanks for the explanation, but I still don't quite see how this is special, afaik LDF is analogous to van der Waals force? Is this basically the same as a "loose" active site? (Ie. Can bind a range of similar substrates) Is it because the LDF force acts on an allosteric site of the enzyme and thus changes the active site? I also don't understand their use of the term "4D". (Sorry for being difficult, just trying to understand the significance of the paper)
Did that journalist not see the triumphant faces in that picture? Also last I heard, Bazoum was being detained by the coup, not hiding.
Ukrainian grain also predominantly went to western Europe, not Africa.
Sanctions and military posturing from the west probably doesn't help. Seems a bit rich to me to sanction China and then be annoyed you can't get your economy bouyed by them?
But the initial stimulus is binding to the substrate, which then catalyses the reaction, which afaik, is how all enzymes work. I'm just wondering what is special about CYP450s in this case. Also, what are the multiple functions? Surely the entire organism itself is a better example of a soft robot
Flagrant racism on multiple levels, it is horrendous to see it flaunted in broad daylight. They say first one racist thing and then back it up with orientalism.
Couldn't access this link so used another one I looked up, but I'm not really sure what the point of this was, what they state are common features of enzymes. I suppose they are referring to how the same principles could be used to create soft robots?
I am indeed talking about consumer high-end cycling, and I see it poisoning peoples minds in my city with their marketing that says to be eco-friendly and cycle to work you have to buy a brand new bike for £1000. I am arguing about the case in my city and the direction I don't want to see cycling in general take. I agree with you that in many places, cycling is much better, the Netherlands is a great example. I am not going after cycling as a whole, just the rich directors of Shimano, SRAM, Trek, Specialized, etc. that have greenwashed expensive high-end cycling and make people believe that they need the latest stuff. I am not saying that the industry is already in a bad place, just that it could head that way.
I would argue the difference between modern bikes and old bikes for short to medium commutes (<1 hr) is immaterial. I have commuted on a carbon racing bike, an aluminum gravel bike (~£500) and a ~40 year old steel road bike I got for £20. Of course the carbon bike is very light and fast, but it has a massively greater ecological and financial cost. The aluminium gravel bike is pretty nice to ride, but not significantly different to the steel bike, which I actually find more comfortable on the road. The rotors on the gravel bike will soon need to be replaced, and that will probably be £100. I would agree with you that some modern components are better, notably corrosion resistant chains and puncture-resistant tyres. I would disagree on repair costs, in my experience, a repair at a shop in my city will cost at least £30 for something very simple like a new chain (which I can fit myself for less), and a while ago I had to pay £60 to replace a Di2 cable that got severed. (It went through the BB and I don't have the tools to take out and refit a BB).
I'm not arguing against a strawman, I'm arguing against an extreme case. In the city where I live, people buying loads of fancy new expensive bikes to seem "eco-friendly" is large. The number of high-end bike shops is large. Repair costs are extreme; £60 for a medium job. This is of course, a predominantly white, affluent city. I regularly see new gravel and commuter bikes (the latest trend) manufactured by the likes of Specialized, Trek, Canyon. These cost in the region of £1000 +- 200. I agree that there is not mass migration away from standard parts yet, but I am worried that that is the direction the cycling industry wants to take. There is already an explosion of different cassette standards, meaning you need unique tools to change many of the new cassettes. Disk brakes add complexity and expense, and your average commuter bike arguably does not need disk brakes, they are just a shiny addition to make it more marketable. My argument is against the increase of these expensive bikes, fancy parts and brands that produce them, as it just pushes people away from cycling and the ecological and health benefits it can bring.
Psychopathic, how can a politician like this have any popular support