I’ll definitely try to have off days! I’m a full-time high school math teacher right now, so I don’t have a lot of free time to begin with. But all the more reason to have a schedule then!
I can't say I know the answer, but I do know that one of these bugs -- Tardigrades -- are extremely hard to kill. IIRC one was put into a vacuum and removed after some time. It was either completely fine right away or after a little while.
If I had to give a guess to other things, some of them probably die, yes. Hopefully someone else who knows more will be able to give more information!
Feel free to infodump. This sounds interesting.