Skip Navigation

InitialsDiceBearhttps://github.com/dicebear/dicebearhttps://creativecommons.org/publicdomain/zero/1.0/„Initials” (https://github.com/dicebear/dicebear) by „DiceBear”, licensed under „CC0 1.0” (https://creativecommons.org/publicdomain/zero/1.0/)HE
Posts
0
Comments
271
Joined
2 yr. ago

  • Im not in charge of the checkbook, but I do place purchase requests. I also am in charge of reducing direct labor and know what our overhead numbers are. We are a small company though. It should be possible to reduce overhead in larger companies due to economies of scale, however, it is not always the case as the bureaucracies required to interface with the FDA are not trivial.

    I was involved with a product transfer for a large company one time. Due to the small volume of the product and the complexity of Sustaining and reporting activities it had a 60% overhead. I did look at the books on that. While that's an extreme case, I've also seen product launched with 40% yield. One device I worked on was a stapler for the heart. We had to load the tiny staples into the device, fire it, evaluate the staple formation, then reset and reload the staples. It had about 80-90% yield if I remember correctly.

    These aren't roast beef sandwiches. People die if you fuck up.

  • I work in med device, close to pharma, but a bit different. There is a lot of overhead. Beyond all the validations required for startup of each line, there is quite a lot of Sustaining work.

    I'm not trying to defend this price, or the gouging that pharma does regularly. But I don't think the $5 price includes all the overhead of the QMS.

  • I'm not a fan of Paltro, but... Really?

    Do you honestly expect a YouTube channel that makes mid to moderately famous people eat spicy food to be a paragon of journalistic integrity? That's just silly.

    Also, yes she is parody of herself, but personally I reserve that level of vitriol for the Bezeoss and Rumsfelds of the world.

  • I remember having to rewind the cassette then hitting reset on the counter, then fast forward to the place on the tape where your program began then entering LOAD then pressing play... All for the crappiest artillery game...

    https://en.m.wikipedia.org/wiki/Commodore_Datasette

  • When COVID shut down my state (we were considered essential) we got furloughed one day a week. I was getting paid less so I was concerned, but it was honestly the best thing to happen to me. We started a garden, I got so much more done. I was healthier and happier.

    Going back to 5 days a week, and longer commute (no more COVID clear freeways), I can absolutely feel my life shortening. I've gained a ton of weight, and increased stress significantly.