Eiri @ Eiri @lemmy.world

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11 mo. ago

That's pretty impressive. I hadn't even thought oral treatments were possible!

It's amazing.

Well that's what I get for not checking my info!

Thanks for the correction.

Are we both talking about the original game for Nintendo 64? Because that sounds like a bit of an overstatement to me if that's the case.

Or am I remembering something wrong?

Oh that probably helps!

I do have a few issues with it:

• the grippy texture underneath is a bit much. It holds on to grime really well and it's a challenge to clean. I'm not sure we actually needed a grippy texture at all to begin with, but if we did, I wish ease of cleaning had been a bigger concern.
• the buttons under the controller and L2/R2 buttons are a tad too easy to press by accident.
• The L2/R2 buttons are not ergonomic enough. I can tell the intent is that I put my indexes on L1/R1 and middle fingers on L2/R2. But it's uncomfortable to do that due to how much the L2/R2 buttons stick out. My hands just aren't that big, and even if they were, I just don't think it's a very natural position to outstretch both fingers like that. It puts too much strain on the ring and little fingers. So instead I only use my indexes for both triggers. Thankfully games rarely need you to do both at once. I wish L2/R2 were lower instead of trying to be flush with L1/R1.
• I don't play car games, so the gradual triggers are nothing but a negative to me. They reduce my effectiveness when parrying in Elden Ring, for instance. I know most people do care about car games though so I don't know what they could have done about that without worsening reviews...

It's clickbait. They do this because it brings in more income. I don't resent them for it. Flying what they can to make sure more people watch it seems fair to me v

They got paranoid about nuclear and closed down all their nuclear plants. They intensified fossil fuel power production because they didn't have enough renewable power. Then prices went up due to the war end they had an oh shit moment.

Doesn't look bad at all, but aren't Paper Mario and Mario & Luigi series RPGs?

Feels weird to use them as examples for inspirations for a platformer.

Feels more like Yoshi's Island elements thrown into a 2D version of Super Mario 3D World.

I bought one for that purpose. Realized it's too much, the angles are so large I can't hold it for long periods without hurting my wrists, and it's really heavy, compounding the wrist pain issue. Also the triggers have way too much resistance.

Plus the battery life is really short.

I ended up buying an 8bitdo Ultimate. Much better.

Elden Ring. Welp, at least I guess i revive on death now?

It must have been over 5 years ago. It turned me off. The culture there was so painful. People would refuse to answer a question just because they deemed the premise of your question unacceptable. Or even recommend you change your whole project's language.

It was like that both in questions and in chat. I never tried again.

Okay off topic but I had to Google "gubernatorial". That word looks made up.

I wish you were wrong. But...

CRISPR makes gene editing easier, but unless you've got a way to deliver it to every cell, it won't do much unless you're targeting such a small number of cells that it's realistic to have a technician physically inject it into a cell.

That would work for an embryo. Ignoring the plethora of ethical issues and the lack of data on long-term effects, it would probably be pretty easy for a scientist to make the change in an embryo and then go through the normal in-vitro fertilization procedure.

For a whole organism, though, it's more difficult. One obvious solution is a specially modified virus, and that's under research.

There's a lot of stuff here if you want to dive deep:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356196/#sec3-biomolecules-10-00839title

It's speculation, but from my experience with Accutane I can infer the following possibility:

• an earwax blockage could get worse because of dry earwax depending on the particular ear

Also speculation:

• if there's fewer lipids in sweat, you keep those fats, and potentially you lose less weight.

We hadn't heard of the game. It's not that it won't sell, it's that it wasn't advertised before now.

A Climate Town video convinced me natural gas actually manages to be worse.

Natural gas is methane, and it's extremely hard to handle that without having any leaks, ever. And since methane is a very powerful greenhouse gas, it doesn't take that much leaked gas to cross the line into "worse than coal".

And there are lots of leaks.

Well there's a pretty easy fix unless it's an extreme case. Razor and antiperspirant (or just deodorant if you're worried about aluminium).

Maybe she's used to it. Maybe it's not that bad to her. Or maybe she just thinks it's impolite to point it out.

Maybe you're right and you really don't smell much. But most cases I've seen actually did smell.

For a few months, while I was taking Accutane, my earwax turned dry and flaky. It was awesome. It would come out much more easily, it wouldn't accumulate, and for once my ears stopped producing so much liquid. But I imagine depending on your unique body, it could make things quite a bit worse if you manage to get an earwax blockage.

Disclaimer: do not take Accutane for more than a few months, unless your doctor really knows what they're doing. Apparently there are significant risks associated with long-term usage.

And pure speculation, but I imagine if you're not excreting that fat, you might lose a tiny bit less weight when exercising?