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InitialsDiceBearhttps://github.com/dicebear/dicebearhttps://creativecommons.org/publicdomain/zero/1.0/„Initials” (https://github.com/dicebear/dicebear) by „DiceBear”, licensed under „CC0 1.0” (https://creativecommons.org/publicdomain/zero/1.0/)MI
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2 yr. ago

  • You're right, and an upvote for you. I've seen colleagues who encounter a 90% drop in efficacy when making the leap to Phase 1 trials (and this is excluding safety concerns!).

    It is rigorous and thank everything the Process is put in place. But I specifically used Oxycontin as an example for a pertinent reason. Rigour isn't applied to everyone equally, and I think that itself underscores a need to think critically.

  • I agree, we should probably trust the doctors more than the crazies on Facebook or wherever they get their nonsense. But I think it's also dangerous to place blind faith in doctors, who themselves are susceptible to misinformation and advertising. Oxycontin adverts appeared in NEJM, doctors went "wow I should prescribe that", and that didn't go well.

    I think trusting Science is most important. Read peer reviewed articles and read them critically.

  • Tunic is amazing! Although the combat feels very clunky (maybe I'm spoiled by sekiro).

    Thankfully, you can just turn on reduced difficulty, since the beauty of the game lies not in the slow combat, but the puzzles and puzzles within those puzzles. Also the main character is adorable.

  • I think the people who downvoted you don't actually understand that this is really Malaysia being antisemitic. This is a country (my country, mind you) that has a term for the Jewish Agenda (Agenda Yahudi), and thought that the vaccines were haram because the Jews were purposely putting pork serum into it.

    I'm against Israel as well, but you'd think people would have some nuance when discussing topics like these.

  • Yeap fully agreed here as well. I do think the medium itself is shackled by its own chains, but my goodness when you find a game that does it well -- the feeling is astounding.

    I guess it depends on the player as well. I adored how TLOU2 handled its story but most people might disagree.

    Anyway, I've come to the realisation that I've mostly been reading non fiction lately! Maybe that's why I'm so fiction starved.

    If you've any books to recommend I'd love to hear them!

  • I'd like to think I'm an avid reader (and gamer) as well. I view both highly and both have their strengths.

    SPOILERS

    Video games shine in terms of player interactivity. I genuinely felt visceral, strong emotions by simply having to press the square button 3 times in TLOU2. Bashing someone's head in is the only way to proceed. The music gets more distorted, the screen itself becomes blurry -- I felt as Ellie felt. Distraught, upset, angry, and everything else in between.

    I felt the acceptance that I have been honing in my countless loops of Outer Wilds when I finally pulled the system's "life support" out. Flying through space one last time while the music echoes this final journey really made me feel things.

    I'd summarise the edge video games have as "This is what you (the player) have done. You have agency. Deal with the consequences of your own actions, or reap the benefits."

    A huge disclaimer, I know that the story is already established in the writers room. I'm not saying that games allow you to craft your own story. I'm saying that they allow you to craft your own experience.

    Of course, great writers can accomplish the same. I love Atwood's writing in particular, and she does conjure up wonderful emotions. But you always feel for someone or something. You don't have any agency in what happens, so emotions tend to be dampened as well. That's my personal opinion anyway, feel free to disregard it!