fracture [he/him] @ fracture @beehaw.org

Posts

2

Comments

149

Joined

2 yr. ago

really good. IUD insertion wasn't too bad for me, but i def would have still taken a local anesthetic for it if it had been available. this is also probably huge for people with sexual trauma and stuff

oh okay, sorry, i took away a different impression from your OP talking about how the FDA process is flawed due to appeals being the starting point (which very well may be true) - but including that with this article made it seem like you felt that way about this particular incident (e.g. the link was supporting evidence), not that the commentary on the FDA process was it's own, unrelated thing

glad to hear that we're in agreement about the denial, though

i can't really comment on the process, i've never taken mdma myself. that said, you say there's no way you wouldn't know you're on it, but there's a number of substances out there where you'd think that would be the case, but it isn't (think like, the stereotype of people acting drunk with little / no alcohol, just thinking they had it). also, the dosages may be lower / less obvious, although i have no idea what the dosages used for recreational use vs for therapeutic use are here

idk dawg this seems pretty sound according to the article

The FDA and its advisors identified flaws in the design of the clinical trials, missing data, and a variety of biases in people involved with the trials, including an alleged cult-like support of psychedelics. Lykos is a commercial spinoff of the psychedelic advocacy nonprofit Multidisciplinary Association for Psychedelic Studies (MAPS).

FDA advisors also noted the public allegations of a sexual assault of a trial participant during a Phase II trial by an unlicensed therapist providing the MDMA-assisted psychotherapy.

...

On Saturday, using the existing data and scientific literature to support MDMA therapy got a little more difficult for Lykos. The journal Psychopharmacology posted retraction notices for three studies that involved Phase II clinical data of the therapy. The studies included a 2019 rationale for a Phase III trial design, a 2020 pooled analysis, and a 2020 study on how antidepressant use may affect the response to MDMA therapy.

The retraction notice cited two reasons for the retractions, including "protocol violations amounting to unethical conduct" at one of the clinical trial sites—a reference to the sexual assault allegations—and undisclosed conflicts of interest by the authors.

like. these are pretty good reasons for not going ahead. it's on lykos and the scientists running the trials for not keeping their paperwork straight and, you know, not warning people about the risks of the study

from an article cited within (https://qz.com/1809184/psychedelic-therapy-has-a-sexual-abuse-problem-3):

A few years ago, a therapist working in a MAPS MDMA study publicly spoke about his challenges dealing with a patient’s sexuality. Early in his career, Richard Yensen was working with a “lovely young lady who became very sexualized in her relationship around the [MDMA] sessions,” he told an audience at California Institute of Integral Studies in 2016. “It got so intense,” said Yensen, that the chair of his department saw him mid-therapy session and told him to leave the room, warning him to always have another therapist alongside him during sessions. “And thank god, because she became more and more and more activated sexually,” said Yensen. “I don’t think I could have handled it.”

Not long after, Yensen was accused of sexually assaulting a PTSD patient, Meaghan Buisson, during a MAPS clinical trial on MDMA

like. even GENEROUSLY assuming that nothing truly unethical happened. this is a huge issue that will only get worse if it's made publicly available

i'm not taking a position on whether or not it should be made available as a treatment. i don't know and i'm not qualified to determine that. but given what's been said, it feels reasonable to want more data and perhaps go "hey think you could run a trial without getting accused of assaulting people?"

nein

can they just please make a lower budget game for the sake of branching out instead of pushing millions into a game expecting it to explode in sales? no? too much to ask? ok...

LOL it's been me before but hopefully never again. sometimes it feels like that though, when i'm thinking about something or someone really hard for a while :')

instead of learning to stop over thinking and being less anxious, i've decided to lean into it and try to prepare / predict every situation, along with the most common / reasonable ones, and prepare accordingly. and once i have, i let it go

for example, i'm at the airport to take a flight soon... so i packed earlier today to the best of my ability. both for necessities and entertainment. is it possible that i forgot something? you betcha. but according to all of the possibilities i've simulated in my head, i've got everything i need within the possibility sphere i'm likely to occupy

of course, there are some situations which could happen that i would be screwed if they did... the most concerning of which is, embarrassingly, whether or not my nose hair gets long enough to make my nose itch while i'm gone. but hopefully that was a one off itching that won't come back later!

the possibility space of a trip away from home is pretty small and tame, but the possibility space for interactions with other people is much bigger, as well as unique to every individual. plus, the ever present threat of a traumatic reaction adds a lot of randomness to the scenario

still, i'm hoping that i can build a broad, general enough map to cover most situations. it's quite a herculean task, but i feel like humans are mostly the same at heart. guess i'll find out if that's true or not 😅

please note that relaxing and accepting the possibility of things going "wrong" (in unforeseen or undesirable ways) is still a very important part of the process. for the best results, you'll still want to be able to take in, process, and respond to any given situation, which you'll need to be able to accept and calm down to process in the moment

the key difference here is recognizing that the main way a social interaction falls apart is when a traumatic reaction occurs, and researching and recognizing what that looks like, and understanding the mechanisms at play behind it, and the best ways to act and respond when it happens; while also taking into account that you, yourself, may have a traumatic reaction in response, with the associated skillsets learned and developed to counteract it

so yeah, writing all of that out is why my brain is a little funny. i don't really think i should, because it feels like i'm talking a little bit too much, either about how i work, or how people work, i'm not sure. buuut i'm at the airport and a little tipsy and have nothing better to do... and you asked! so i hope it was kind of a fun or interesting read

flail time

yeah i feel you. i don't think this would be better even if i were vegan (i'm not bc i think i would starve due to a number of dietary restrictions /allergies, but i cycle in the vegan food i can)

lmaoooo believe it or not, some people around here ALREADY had that idea. which is INSANE when people are paying >$100 a month in HOA fees 😭 which i discovered by talking to someone i (mistakenly) believed was getting paid to pick up trash in the area

it's shit like that that makes me want to organize people

this is interesting to me. i recently met, and subsequently turned down, a local communist party. after some interrogation, i realized that, much like organizing folks in my workplace, i wanted the work i did with them to directly benefit the people of my community. they were very much about recruitment ("waiting for the next event where capitalism radicalizes a bunch of people") and learning theory (... which i respect to a certain extent), with a distinct emphasis on doing things other than community building / mutual aid / etc. they're also mentioned as one of the not-great groups (RCA)

i guess i'd like to know which groups are doing that important community building / solidarity building / organization education outreach? there's a mutual aid group in my area i'd like to become involved with at some point, at least

to a certain extent, i also want to know if my criteria for judging a group is good (or, if you agree, i suppose) - i've always thought that the worth of a group (here, meaning, a group meant to change things in the world for the better) is measured in the lives they've changed. but i can't prove that, obviously, it's just what i've arrived at based on my experience of the world, and i'm curious what others think

a friend of mine discovered the tip to add "before:2025" (or, the current year+1) to your yt search to improve it. i have no clue why that does anything but it reverts it to pre-enshittified functionality

it's crazy how those comments are aging like milk precisely because google/web search is going to shit (in addition to being dickhead comments ofc)

just weird to look back and think about how we thought it would never change

fwiw you've conveyed the same general question i have about the situation, albeit far more eloquently than i would have been able to

i am totally down to stop using words that disabled people find offensive, but i need alternatives to express that someone is being needlessly / purposely ignorant or otherwise harmful and is generally worthy of scorn and contempt

which isn't to say that providing that is the onus on disabled people (it's really not, their only real obligation is to express their experiences)... but it does make it a lot easier to action on the request

it's also kind of interesting to approach this conversation both as an outsider, but also as someone who these words do apply to in some capacity

interesting to consider that third places can be virtual in this day and age. i wonder how they compare in terms of healthiness... probably better than not having a third place but worse than an in person one, if i had to guess

hate speech (of which nazi speech is a subset of) isn't political either. it definitely should be banned because it demonstrably causes people to get hurt

insane stance to be advocating that nazis should have free speech in 2024

oh that's crazy, i saw that syntax (from my client) and went, no way that's correct (bc of the empty square brackets). but it being alt text makes it make sense, thanks!

looks like my alt text is breaking it for me tho (it's removed in the above embedding)

https://beehaw.org/pictrs/image/717d18ed-533a-461b-975f-e2e1dc26b720.webp

i don't know how to embed pictures but hopefully this works ^^; i've been seeing this one around lately and i think it's very funny

really good article

make sure you do your online illegal activity AND RESEARCH ABOUT THOSE ACTIVITIES behind a VPN

if you need to communicate with other people about illegal activity, do it behind an encrypted service like Signal

illegal != immoral

stay safe out there folks

✊🦎