ericjmorey @ ericjmorey @beehaw.org

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10

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210

Joined

2 yr. ago

That title left me wondering if I even understand English.

The idea that long living organisms can unlock methods to extend human life has been science fiction for a long time. It's exciting to see actual research in that direction. The actual science is always more mundane than science fiction.

the researchers used techniques to “downregulate” or quiet down the activity of TEs. When they did this to specific TEs in worms, the worms showed signs of aging slower. Even more, when multiple TEs were controlled simultaneously, the lifespan-extending effects added up.

“This epigenetic modification may pave the way for a method to determine age from DNA, providing an accurate biological clock.”

Almost anything seems to qualify as appropriate for this Technology community. It's hard to think of something that's not "technology" making this a general purpose community. Which is fine if that's what people want, but I'm probably going to unsubscribe if there isn't more focus here.

They were assigned to study rat erections.

Mozilla is implementing Manifest V3. They plan to implement it slightly different than Chrome: https://blog.mozilla.org/addons/2022/05/18/manifest-v3-in-firefox-recap-next-steps/

They have published a guide for extension developers: https://extensionworkshop.com/documentation/develop/manifest-v3-migration-guide/

More background on Manifest V3:

https://www.eff.org/am/deeplinks/2019/07/googles-plans-chrome-extensions-wont-really-help-security

https://www.eff.org/am/deeplinks/2021/11/manifest-v3-open-web-politics-sheeps-clothing

https://www.eff.org/am/deeplinks/2021/12/chrome-users-beware-manifest-v3-deceitful-and-threatening

https://www.eff.org/am/deeplinks/2021/12/googles-manifest-v3-still-hurts-privacy-security-innovation

Shouldn't this be in a political community and not Technology?

Network effects are always what drive online services.

Tenants have more legal rights as well compared to those that simply agreed to whatever terms an online service made up.

Mastodon is not a one to one replacement for Twitter and doesn't intend to be. Mastodon is nothing like what many (or even most) people who use twitter want.

Mastodon has a lot of issues that it is still working out that make it a worse experience than pre-musk Twitter.

Why?

I don't think so.

This whole thing has the smell of Microsoft pulling the strings to gain more control over the bleeding edge of AI. Idealists losing out to cold capitalists seeking profit and control is something we've seen many times before.

Content of the letter as reported by Wired.com

To the Board of Directors at OpenAI,

OpenAI is the world’s leading AI company. We, the employees of OpenAI, have developed the best models and pushed the field to new frontiers. Our work on AI safety and governance shapes global norms. The products we built are used by millions of people around the world. Until now, the company we work for and cherish has never been in a stronger position.

The process through which you terminated Sam Altman and removed Greg Brockman from the board has jeopardized all of this work and undermined our mission and company. Your conduct has made it clear you did not have the competence to oversee OpenAI.

When we all unexpectedly learned of your decision, the leadership team of OpenAI acted swiftly to stabilize the company. They carefully listened to your concerns and tried to cooperate with you on all grounds. Despite many requests for specific facts for your allegations, you have never provided any written evidence. They also increasingly realized you were not capable of carrying out your duties, and were negotiating in bad faith.

The leadership team suggested that the most stabilizing path forward - the one that would best serve our mission, company, stakeholders, employees and the public - would be for you to resign and put in place a qualified board that could lead the company forward in stability.

Leadership worked with you around the clock to find a mutually agreeable outcome. Yet within two days of your initial decision, you again replaced interim CEO Mira Murati against the best interests of the company. You also informed the leadership team that allowing the company to be destroyed “would be consistent with the mission.”

Your actions have made it obvious that you are incapable of overseeing OpenAI. We are unable to work for or with people that lack competence, judgement and care for our mission and employees. We, the undersigned, may choose to resign from OpenAI and join the newly announced Microsoft subsidiary run by Sam Altman and Greg Brockman. Microsoft has assured us that there are positions for all OpenAI employees at this new subsidiary should we choose to join. We will take this step imminently, unless all current board members resign, and the board appoints two new lead independent directors, such as Bret Taylor and Will Hurd, and reinstates Sam Altman and Greg Brockman.

I don’t think anyone except for employees there know

I wouldn't even bet on that. It seems that no one has a full picture of what is going on.

What city are you talking about?

GoodRx is not covered under HIPAA. It's the reason why it and companies like Postmeds exist, to skirt limitations on data collection and selling imposed by HIPAA. The fact that the data leaked is more of an issue for profitability of those companies than a privacy breach for Americans. The people who are using these services in a desperate attempt to access affordable healthcare have no legal expectation of privacy already.

What an absolutely disrespectful comment about someone that attended Dartmouth's engineering school, worked at Goldman Sachs, an aerospace engineering contractor, Tesla, a tech startup that had a successful exit, and has been the CTO of OpenAI for 5 years. Somehow none of that matters because while she was able to do all that, she also might have given birth to and raised a child?

I think you need to reevaluate how you see the world.

Whidrawal rates are a simplification the same as growth rates. They should not be expected to be constant. Withdrawals tend to be absolute (with some flexibility like not taking a trip or not renovating a kitchen or deck) rather than relative to market gains. Also withdrawals can be made in a way that changes your asset allocation (don't sell your equities in a downswing, sell your fixed income assets for needed liquidity)

All that said, I'm going to read the article now and see if they hit on any of those points.

PS Dave Ramsey is who idiots think is smart, so I pretty much disregard what he says as he says it.

This feels like it's not appropriate for the Technology community.

I'm interested to see how that's implemented. I remember interacting with Facebook via email a long time ago.

Fixed