cleanandsunny @ cleanandsunny @literature.cafe

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2 yr. ago

This is a question for your doctor, so I am not providing any medical advice. Typically whether from infection or vaccination, we expect to see protective antibodies for several months.

It’s one patient and these rapid changes happened before in human patients, so who knows. All other H5 outbreaks to date have been limited and sporadic. We’d need more genomic data from more human cases. They are also going to monitor these cases closely so we’ll find out more as we go.

You’re welcome!

I knew this question would come up and unfortunately (or fortunately) I’m not an immunology PhD 😅 of course it’s always recommended to get flu shots due to partial coverage, reducing coinfections, and sparing health systems undue burden but let me see if I can get you a proper answer from someone who dreams about proteins and titers.

The former! I’m not currently worried about contracting it, and neither should anyone who isn’t hanging out on an animal farm. That said, of course flu and other viruses can jump species, and flu mutates a lot faster than some other viruses. There is never any way to rule out a wild flu mutating into something that can impact human health more broadly.

To your second point about goalposts moving - I’m not sure specifically what you’re referencing, but perceived risk is inherently personal and can never be a one-size-fits-all calculation. We might have a tidy risk ratio in a paper that pertains to a certain population, but it doesn’t always translate to the general public. Typically we leave that stuff to CDC, because they have whole committees full of brilliant people to synthesize the evidence and argue about what to tell the public and how. Science changes and so do recommendations as we learn more. I would recommend getting further H5 “news” and updates directly from CDC. You can sign up for the MMWR which will have weekly stats and case details.

Former influenza epidemiologist here and the answer is probably not. Our current influenza vaccines in the US (and in almost all countries) are trivalent, meaning they have 3 strains: an influenza A H1N1 (aka swine flu), an influenza A H3N2, and an influenza B (Victoria). Fun fact, they used to include 4 strains, but COVID actually wiped out the second B strain and it hasn’t been detected since 2020.

Unfortunately, the current bird flu is H5, a separate influenza A strain. Typically there isn’t a lot of shared clinical protection overlap between genomes this different. This is why influenza vaccines typically use 3 (and formerly 4) different strains of the virus, to confer the most protection.

However, unless you work in dairy or poultry, I would not worry. I am not particularly worried. I know it’s making headlines, but only 66 human cases are in the US so far, and all but 2 had direct contact with those animals. Currently there is no documented person-to-person transmission and certainly nothing like what we saw early on with COVID.

If you want my personal take, I still mask at large events / crowded places / airplanes to avoid flu and COVID altogether. I still encourage everyone who is ill to mask and stay home, even though it’s out of fashion. I think we will see egg, dairy, poultry, and beef prices rise with H5, as farmers are forced to cull animals. Also, we may see cases from raw milk and backyard animal husbandry - please don’t drink raw milk, pet cows, kiss chickens, touch dead birds without gloves, etc. right now and you probably won’t get bird flu.

Hope that helps, happy to answer any other influenza or respiratory infectious disease Qs!

Edited to add: The fact we have human cases at all is because farm workers - usually immigrants with limited English - are routinely exploited, denied PPE, or put at risk in unacceptable ways. Farms are basically self regulated in the US, though they are officially regulated by the USDA. It is extraordinarily difficult to get farms to cooperate with pandemic preparedness. You have to pay them federal money to do anything. There have been documented cases of farm workers being told to cull infected birds with zero PPE, and that’s unacceptable. These vulnerable people are the ones paying the price for our H5 knowledge right now, and it’s not right. It’s disheartening to have worked on pandemic preparedness for decades, fumble COVID altogether, and still fail to prepare for the next one. As climate change continues unmitigated we expect to see more human-wildlife interaction and more zoonotic diseases. We can’t just do good science; we also must address workers’ rights, capitalism, and climate change.

Yes, what Smoogs said! I use washes a lot - which means a lot of water on the paper - so wrinkling has been a constant problem with other papers. These are 100% cotton so it absorbs water much differently compared to papers made with wood pulp.

I splurged on some really nice watercolor paper blocks (Arches cold press), tested them today and I’m obsessed.

• Ireland and Italy offer citizenship by descent, but it is a long process
• The Netherlands and the US have a treaty called DAFT that allows you to start a business in NL
• France offers a self employment visa
• Check skill shortage lists for countries of interest - almost all European countries need skilled trades, truck drivers, etc. that wouldn’t require a degree
• Study abroad; it’s possible you could apply and receive funding for a degree since many countries have free education + work study arrangements for your living expenses
• Teach English abroad
• Look at international NGOs, you could possibly get hired as an admin/etc. without a degree but that might be a stretch

We have similar taste and you need to listen to Kalush (and Kalush Orchestra) - Ukrainian hip hop! The “Orchestra” group has more folk influences but all of it is just banger after banger. I don’t understand a word of Ukrainian but I love these guys.

Not a “song” per se, but Black Thought freestyling effortlessly for like 10 minutes straight is impressive AF: https://youtu.be/prmQgSpV3fA

For context, that show asks everybody to freestyle and some refuse, some do a few bars, but nobody goes for 10 minutes, lol.

For an actual song, and you wanna talk art, Blackalicious - Attica Black. Really love the sampling and the musicality of it, there are so many layers and it’s fun to listen to. https://youtu.be/qHRxorG8ABs

If anyone has ever worked or talked with a refugee or asylum seeker, none of this is surprising. The US gives so little assistance to resettling refugees that it’s truly embarrassing.

They get three months of bare minimum help - often through religious “resettlement” groups who receive the funds. After three months, they are expected to get a job, pay their own rent, navigate life in the US (including driving), and speak English well enough to do all of that.

They get almost no extra healthcare, rent assistance, food assistance, trauma therapy, or anything else beyond that point unless they are able to navigate the systems to do so. And to be honest, that is difficult enough for someone born here. It’s almost impossible for a new refugee. What little assistance they do get after the first 90 days is often due to community and church groups, not the US government.

Theoretically, they have case workers etc. through the resettlement agencies, but it’s a total mess. It’s an absolute disgrace, and we can and should be doing better to support refugees and asylum seekers. Especially if they are going to get dumped in a small town with no resources. I really understand residents’ frustrations, but I also hope this ugly episode teaches people how woefully inadequate our refugee program is - and helps them advocate for change! We can do better.

I think others have covered the economies of scale and niche products creating the disparity.

But I wanted to suggest that if your grandpa is regularly eating gluten free bread, we have found that making it at home is SO much more affordable than buying a loaf at the store. (Even though gluten free flour is also more expensive.) Most of the gluten free flours have their own sandwich bread recipe, either on the bag or their website. I don’t know what flours you have access to, but they can be wildly different blends, so using their tested recipes is always best.

We’ve mastered our favorite so it takes only 15 minutes of “work” and then just time in the oven. It’s also much better than store bought! I don’t know if that’s possible for you, but it could be a lovely weekly ritual for you and your grandpa.

Also, to anyone suggesting we just eat rice and beans, I’m an old celiac. We went without bread, pasta, cake, pastries, cookies, brownies, pizza, and crackers before these products came to market. These are mostly “fun” foods that I don’t eat regularly, but usually pop up in social situations. Do you know how many sad birthdays with no cake we’ve had? How often we’ve watched our friends and family eat things we could never have? I am so grateful to the “fad” gluten free people who made it possible to have culturally/socially important foods we were missing out on for decades!!

Oh yes, ours is a chair thief too! Little stinkers.

Our 15 year old has a new habit of coming into the kitchen every time we do, and stretching out directly in the middle of the walkway so he is in the way at all times. We have a pretty decent sized space, but he’s a very long cat when he wants to be. I feel like he defies the laws of physics because I don’t understand how he’s in the way literally everywhere. It makes me crazy.

So when we cook, which is usually 2-3 times a day, it’s like, need to open the oven? Cat. Need to get into the fridge? Cat! Sink? Cat. Oh, I need to dry my hands? Cat. We have definitely stepped on him by accident since he started doing this, but he’s still undeterred. He has bad arthritis, so I don’t mind when he sits in front of the oven when it’s on, because at least that one makes sense. (He has multiple heated beds too; don’t feel bad for him.) But it’s like, I would love to be able to grab water from the kitchen or feed the dog or do literally anything in there without almost stepping on my cat.

My pleasure. Let me know if there are other resources I can recommend!

We ALL need to hear it! You’re so welcome. I try to keep reminders near me when hustle culture rears its head, and it always helps :)

I always find that starting any new job is exhausting! There is so much to learn - not even the “work” itself, but processes, personalities, and systems that differ from workplace to workplace. Unless you are struggling hard financially, give yourself some time. For me, it takes at least 4-6 months in a new job to feel ready to add something else. (Now that I own my own business, it’s just adding the next thing in the business…then 4-6 months later, the next thing…). You will have to feel out your own balance and where you can draw the line. I don’t think it’s a bad idea to make more money, if that’s a goal. But you can’t do it at the expense of your sanity, relationships, health, etc. Make it sustainable.

I’m in the US for context, but have lived all over the world, and don’t participate in the hustle culture here. I work hard for my clients and there are crunch times, but on average it’s about 30-35 hours a week. That’s a sweet spot for me! I hope you find yours.

Willpower IS a thing and there is some really interesting research about how it is an exhaustible psychological “resource” we have! In other words, we can exercise our willpower up to a point, but it’s not infinite. Highly recommend reading “Switch” by Chip and Dan Health which goes into willpower as a concept if you are interested in this.

I don’t know about the notes, but I wanted to say that it takes time and effort to unlearn this idea that we are supposed to be productive all the time. This is a lie that many powerful people want us to internalize so we work ourselves to death, and it’s very insidious and omnipresent. It’s become a perverse “value” in our society at large and something to be proud of.

But you are not a machine. You’re a person. And that means you need and deserve rest and comfort.

You have inherent worth outside of your productivity, how hard you work, or how much money you make.

Those metrics don’t tell us anything about how you are as a person, your values, your kindness, your strengths, the joy you bring others.

ALL of that stuff has value. Real true value. You have to start challenging these beliefs about your worthiness. Because you are already worthy.

Some further reading/resources:

1. The Body Is Not An Apology
2. Rest is Resistance
3. Burnout: The Secret to Unlocking the Stress Cycle