The official launcher works through Wine now. In Lutris, it’s the “This is a clean, standard default installation.” option: https://lutris.net/games/genshin-impact/
It’s been a while since I used it, but my choice on Linux was always Quod Libet, which is a smidge barebones but also really powerful (especially with tagging).
Nope! All that option does is install the official launcher, the Visual C++ 2019 runtime, and some fonts. Anti-cheat is untouched.