Not sure about the rest of the world, but the UK version came with a thick manual that didn't just cover the basics like controls and gameplay features, but an in-depth essay on driving techniques and vehicle dynamics.
It was actually really informative from a real world perspective.
High protein intake is common in western societies and is often promoted as part of a healthy lifestyle; however, amino-acid-mediated mammalian target of rapamycin (mTOR) signalling in macrophages has been implicated in the pathogenesis of ischaemic cardiovascular disease. In a series of clinical studies on male and female participants (NCT03946774 and NCT03994367) that involved graded amounts of protein ingestion together with detailed plasma amino acid analysis and human monocyte/macrophage experiments, we identify leucine as the key activator of mTOR signalling in macrophages. We describe a threshold effect of high protein intake and circulating leucine on monocytes/macrophages wherein only protein in excess of ∼25 g per meal induces mTOR activation and functional effects. By designing specific diets modified in protein and leucine content representative of the intake in the general population, we confirm this threshold effect in mouse models and find ingestion of protein in excess of ∼22% of dietary energy requirements drives atherosclerosis in male mice. These data demonstrate a mechanistic basis for the adverse impact of excessive dietary protein on cardiovascular risk.
Here in the UK, our exchange buildings have emergency battery and diesel generator backups so if power does go out for an extended period, then at least the head ends and exchange equipment will still function.
Even a relatively small building will have a backup generator with a 1000 litre fuel tank.
I get it to roughly 303 days from today, which will make a lovely Christmas present.