MaximilianKohler @ MaximilianKohler @lemmy.world

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13

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193

Joined

2 yr. ago

as to effectively use phage therapy you must identify the organism and then select appropriate phages which will kill the bacteria, which takes time that a sick patient may not have without antibiotics

Phage cocktails, FMT, etc... Also, we should get better at speeding that process up if we fund research for it, but we've been instead continuing to rely on antibiotics.

We also haven’t quite figured out how to keep our immune system from eradicating the bacteriophages

Citation? I don't recall that being a thing... phages are ubiquitous in the human body. As much or more so than bacteria. They are the natural way bacteria are kept in check.

NYT undoing years of “finish your fucking course”

WITH CITATIONS.

“finish your fucking course” is wrong, and pigheaded people that refuse to review scientific evidence and reshape their opinions accordingly do a lot of harm and make it impossible for the scientific method to work and for the scientific community to update the public when the evidence and consensus changes.

Everything in here refutes and proves all your claims wrong

Not even close. You seem to be the only one playing games.

When you wipe out all of your microbiome, chances are it returns to normal in the following months after antibiotic treatment.

Harmful misinformation. A plethora of citations were already provided that debunk that claim.

You have to take the full course to prevent resistance from forming.

Harmful misinformation that is contradicted by the citation in the article and numerous other citations that I provided in the OP and my introductory comment.

If you let resistance flourish, then every single time someone needs to take an antibiotic it will be even more likely they develop a C. Diff infection due to the microbiota being wiped even harder.

This makes no sense. I'll rephrase it to make it sensical and accurate:

If you overuse antibiotics, every time someone needs to take an antibiotic it will be even more likely they develop a C. Diff infection due to their microbiota being wiped out previously.

MRSA is actually covered in the cited links. Here's one for example https://academic.oup.com/ofid/article/6/7/ofz288/5522275.

The gut microbiome regulates the entire body, including the immune system and other body site's microbiomes https://humanmicrobiome.info/systemic. You can see what a great resource it is -- very handy to provide categorized citations.

his website is not peer reviewed

Anyone is welcome to contribute and peer review it.

That is not a website doctors look at.

Wrong. Also irrelevant. It contains a plethora of scientific citations, which is all that matters.

Medical procedures are formed and approved through NIH articles with vast testing pools across many geographical areas.

Gibberish that tells me you don't know what you're talking about, but want to sound authoritative.

Yes and no. https://forum.humanmicrobiome.info/threads/doctors-are-not-systematically-updated-on-the-latest-literature-what-t.27/

IMO the future lies in replacing antibiotics with adding instead of subtracting: phages/phage cocktails, FMT, etc. There's also a massive amount of antibiotic overuse for a variety of reasons, including public ignorance about their necessity (lack of) and harms, and emotional thinking and lack of consequences for people in the medical system.

Phages were given up on because antibiotics were an easier solution and the consequences aren't always immediately obvious. But that decision has likely played a major role in getting to the current chronic disease crisis.

That's wrong. Stop confidently spreading harmful misinformation. I already provided citations that you should have checked before making that statement: https://humanmicrobiome.info/antibiotics/

EDIT: And to all the people who upvoted the person I’m responding to, you should not be upvoting people who make medical/scientific claims without a citation, especially when they’re contradicting a highly reputable news source (NYT) that contains scientific citations and expert commentary.

I mean the software I'm running on Win 10. As far as I know, a lot of it still won't run on linux.

Anyway, moot point since people said in this thread that you can bypass the TPM and Microsoft account requirements with Rufus. So anyone should be able to upgrade to Win 11.

There's a lot of stuff that still doesn't run on linux as far as I know.

Yep, I crossposted to two of those already. Feel free to x-post to the medicine one if you want.

Some relevant info I shared yesterday:

While antibiotic resistance gets all the attention, the damage being done to our host-native microbiomes is arguably as big a threat as climate change, as the damage compounds over generations, and once it's gone you can't get it back. (Apr 2019).

Resistance can be solved by restoring lost microbes with FMT: https://humanmicrobiome.info/antibiotics/

There was no nuance in what you posted

This is a flat out lie. The fact that people are upvoting it is very depressing. It's disappointing to see that people on lemmy aren't any smarter than people on reddit.

It says who they are in their signature. And a plethora of peer-reviewed papers are cited.

Only a Sith deals in absolutes. https://humanmicrobiome.info/antibiotics/#antibiotics-overuse

IMO, the lack of ability for nuance is a sign of low intelligence.

Relevant: Antibiotics that kill gut bacteria also stop growth of new brain cells: https://www.sciencedaily.com/releases/2016/05/160519130105.htm

I guess all the people solely cheering for this aren't aware of the damage we've been doing to ourselves with antibiotics:

While antibiotic resistance gets all the attention, the damage being done to our host-native microbiomes is arguably as big a threat as climate change, as the damage compounds over generations, and once it's gone you can't get it back. (Apr 2019).

Resistance may already be a solved problem: https://humanmicrobiome.info/antibiotics/#fmt-to-counter-antibiotic-resistance

4chan's been going downhill for years as well. It's been extremely ban-happy for a very long time. I recently got permabanned for posting a screenshot from Hatching 2022. Something similar has happened to me every time I've gone back over the past 10 years.

Thanks but I don't think this is a good method. We need an addon like RES, or built-in like on Saidit, or a script like this: https://gist.github.com/NathanSweet/de43d5b2cb0c0836763b

Why are you linking to reddit...