Highly recommend Cassette Beasts. It's a monster battler but you can freely swap and collect moves and the level of your monsters are based on your character level and not the level you obtained it. Plus all the moves have affixes like in Diablo that significantly change their use or potency.
The sum of all that means you are always trying out new monsters and move sets, some of which are entirely broken. Great game.
Depending on the complexity of the part either Fusion 360, Tinkercad, or even just 3d Builder. I usually can find something close already existing and just modify that.
As someone who has been in the 3d printing space for awhile, I am amazed at how cheap and featured the entry level printers are. For ~$150 you can get a printer with auto bed leveling and a magnetic bed. At $15/lb of filament, you only need a few projects to pay for itself.
For example, I printed the housing for a USB hub for a friend which is a clone for a ridiculously expensive one that fits Lovesac couches and he paid me $50. It cost ~$2 of filament and ended up printing a few more for others. That alone paid for the cost of the printer.
For anyone who is thinking about it, now is a great time to enter the hobby.
I commented this elsewhere, but to answer your question,
Zolgemsma is a modified version of adeno associated virus and has to be grown under specific conditions. It costs $500k-$1m per production. It's also a one time injection that functionally cures the person of the disease. There are a couple other options but for comparison, the other therapeutic is Spinraza which is an intermittent intrathecal infusion which is $805,000 for the first year of therapy and $380,000 per year thereafter for the rest of your life.
SMA type I also is 100% fatal by year 2-3 and the baby dies without being able to even lift their head. It's a terrible prognosis.
To be clear, I think we should bear the actual costs of research, development, and manufacture as a society and not profiteer off the sick, but there are some contributory reasons for the price.
Zolgemsma is a modified version of adeno associated virus and has to be grown under specific conditions. It costs $500k-$1m per production.. It's also a one time injection that functionally cures the person of the disease. There are a couple other options but for comparison, the other therapeutic is Spinraza which is an intermittent intrathecal infusion which is $805,000 for the first year of therapy and $380,000 per year thereafter for the rest of your life.
To be clear, I think we should bear the actual costs of research, development, and manufacture as a society and not profiteer off the sick, but there are some contributory reasons for the price.
No one has given you an actual reply just assuming that the manufacturing costs for the drug are low. Zolgemsma is a modified version of adeno associated virus and has to be grown under specific conditions. It costs $500k-$1m per production.
I would say Robin Hobb. She writes easy to read, character driven fantasy novels that gracefully deal with a gamut of difficult topics (e.g., orphanism, otherness, sexual violence, mortality, etc.). The books really helped me build empathy for people and concepts that were far afield of my own experience.
I used a coiled cable and put my audio interface to my side higher up on a shelf. That way when I am seated the headphone cable barely touched the ground.
It sounds odd but there was a Supreme Court about it. Essentially someone claimed they shouldn't have to pay taxes on the profits of crime and the Court ruled they did. So they had to create a way for people to do that. For what it is worth, the 5th amendment protects you from incriminating yourself, so you are allowed to decline to provide the details of where the money came from, but it's a bit like paying your parents for something you broke and then just not telling them what it is, and then expecting them not to look around the house.
“it would be an extreme if not an extravagant application of the Fifth Amendment to say that it authorized a man to refuse to state the amount of his income because it had been made in crime. … He could not draw a conjurer’s circle around the whole matter by his own declaration that to write any word upon the government blank would bring him into danger of the law.” .... "It is urged, that, if a return were made, the defendant [Sullivan] would be entitled to deduct illegal expenses, such as bribery. This by no means follows, but it will be time enough to consider the question when a taxpayer has the temerity to raise it.”
It only takes about an hour a week and once you establish a relationship with them you just bring them along when you are doing something fun anyway. You feel a sense of purpose and they fare better in nearly every measurable statistic of emotional well being and academic success. Men in particular are needed to mentor young men and can have the greatest impact. Many organization will match you with a kid who has your same interests too so you're just doing stuff you both like. I really can't recommend it enough.
That's true but the difference is exceedingly small.
According to 1 FDA study, the mean difference for AUC values between test and reference products was found to be 3.5% in the 2-year period following the Waxman-Hatch Act, and 80% of the absolute differences between generic products approved since 1984 and the corresponding innovator products were within a 5% range.
You absolutely must play Doki Doki Literature Club if you have not. It's free. Do not look up spoilers or be put off by the type of game or the setting. Just play it.
P.S. - "Doki Doki" the way you write the sound of a heart beating in Japanese akin to "lub dub" in English.
Yes, without a warrant. It's in the Privacy Notice in any retail pharmacy.
Impersonating a cop is a pretty big step that's illegal in its own right but we did have moms trying to see if their adult daughter was on birth control, but that's pretty easy to stop. Just lock their profile and ask the patient to make up a passcode or only deal with them in person.
Yeah, I didn't say any of that but ok. HIPAA/employers actually require you to give law enforcement information in a variety of situations, including specifically the situation I mentioned:
To report PHI that the covered entity in good faith believes to be evidence of a crime that occurred on the covered entity’s premises (45 CFR 164.512(f)(5)).
I worked at a pharmacy and the only time it actually happened was when a patient tried to sell their Vicodin to an undercover cop outside the store. The cop came in and asked for the information about the prescription and we gave it to him.
The HIPAA Privacy Rule exception for law enforcement purposes, 45 CFR § 164.512(f), permits a covered entity (generally, healthcare providers, health plans and their business associates) to disclose PHI to law enforcement officials without patient authorization under certain circumstances.
Those pharmacies also have this exception listed in their Privacy Policy. I don't like it either, but it is legal.
Highly recommend Cassette Beasts. It's a monster battler but you can freely swap and collect moves and the level of your monsters are based on your character level and not the level you obtained it. Plus all the moves have affixes like in Diablo that significantly change their use or potency.
The sum of all that means you are always trying out new monsters and move sets, some of which are entirely broken. Great game.