There is currently an issue with game sounds in PoE 2 that causes unusual lag.
You can make it somewhat better using in game settings by changing "channel count" to low.
To make it a LOT better, go to (in windows) documents\My Games\Path of Exile 2 -> poe2_production_config.ini and under [SOUND] change as many options to "false" (NOT 0, which turns the volume off, but still accesses the sound files) as you can tolerate.
So, as I understand it, e-ink screens are all made by the same company and sold to the various ereader companies. As such, they are basically comparable. At least this was the case two years ago when I was looking into it.
Huh, I upvoted this and didn't get a ban notice...