Atelopus-zeteki @ Atelopus-zeteki @fedia.io

Posts

2

Comments

1,044

Joined

11 mo. ago

As I understand it, "hidden" is a relative thing. Before exposure one's immune system doesn't know what to look for, after exposure, and immune response, one's T and B cells have a much better chance. That's why denovo immune response to an epitope may not be sufficient, but once the immune system has been 'exposed' or 'educated' the response is much more specific. There are two parts to the immune system, innate, basically structural, and adaptive (T's and B's) that can be primed with certain factors to create a very precise response. The long term nature of immune response is dependent on those cells, which come in number of different 'flavors'. Tissue Resident Macrophages hang out in the area of initial infection, waiting for "that guy" to show up again. They can sit relatively dormant for years. I don't want to mislead, our understanding of the long term memory function of the immune system isn't completely understood. And so we don't know how long a given immune response will last, at least not yet. Does that help? I'm not an immunology prof, or researcher, so I may not have been clear.

Congresswoman Waters, thank you very much for continuing to be who you are, and doing an impeccable job.

Yeah, ignoring a judges specific orders and claiming that you didn't, threatening a judge, that sort of stuff doesn't go over well.

What a lovely coincidence.

Best news I've read all day!

Mutations will always happen, it's what viruses do.

I've learned a lot more about virology, vaccines, and immunology in the past 5 years than I ever thought I would need/ want to know, mostly from listening to the brilliant folks over at Microbe.TV (https://www.microbe.tv/), with This Week in Virology, and the other science based podcasts they produce.

Ok, you're missing a bit here. The "sugar stripping" happens in the lab, during the production of the immunogen, which would then later applied as a vaccine. From there the vaccine induces a response from the immune system, creating antibodies which are specific to the highly conserved part of the stalk structures on corona viruses. As a result one's immune system is prepared for when a corona virus shows up at some point after the vaccination.

What they've found, from the article, and abstract (alas I didn't see any links to full text paper, which may come available after the ACS Spring 2025 meeting), is that they indeed do get an effective broad based immune response against coronaviruses. The 'sugar stripping agent' process is used in the production of the immunogen (basically a glycan stripped version of the more highly conserved spike protein that occurs in all/ many/ a lot of coronaviruses, i.e. which cause common cold, MERS, and COVID19), such that a broad based immune response is evoked when applying it, some time after the sugars (glycans) have already been stripped. Remember the spike is the consistent (conserved) part, and the glycans are the camouflage bits. Researchers have been trying to come up with something based on the spike protein for some time, and this is the sort of breakthrough that they've been working towards. Doubtless more info will be available after the research has been officially presented, March 23-27. (https://www.acs.org/meetings/acs-meetings/spring.html) So it's literally happening now. And may show up on Chi-Huey Wong's google scholar page (https://scholar.google.com/citations?user=GQLirSoAAAAJ) or at Scripps/Sinica (https://www.genomics.sinica.edu.tw/chihueywong/)

Are we talking Weed Mojitos? M'confusted?

I would estimate that as Most Fortunate.

Some people are calling for a forensic audit. And no, it's not getting much press at all.

https://verifiedvoting.org/publication/recounts-audits-2024-verified-voting/

https://www.thecanary.co/global/world-analysis/2024/11/19/forensic-audit-us-presidential-election/

With biodegradeable solar panels, even. And tasty 'fruit' sometimes, too.

Here's the guy's channel, Rich Rebuilds, if anyone is curious- invidious link: https://iv.ggtyler.dev/channel/UCfV0_wbjG8KJADuZT2ct4SA

or yt if you are into that place: https://www.youtube.com/channel/UCfV0_wbjG8KJADuZT2ct4SA

USPS doesn't make money, it's not designed to do so. This standard of profitability is never applied, for instance, to the military.

Frankly, it's an upper class/ lower class situation. Welsh people, historically just couldn't afford vowels. ;-)

Russia proved it by continuing the bombing.

That IS THE SAUCE!

Ooh, nifty wanton destruction of war crimes evidence sounds like a charge that has legs.

No problem, it was a mistake. Now PUT IT BACK, ya bunch a dipshits.