Scientists May Have Figured Out How to Make Fat Cells Burn Calories
Scientists May Have Figured Out How to Make Fat Cells Burn Calories
'may' is my most despised headline word. This article sounds like they may be onto something in mice trials anyway.
Kinda reminds me of dinitrophenol (DNP), another miracle weight loss pill that converted stored calories to heat.
Works great up until it literally cooks you to death.
This new method of converting white fat to brown fat to heat sounds like it's in that same neighborhood.
If it works, cool! But be cautious if you see a bottle of some shit claiming to do this at your local pharmacy.
Wasn't the issue with dinitrophenol not so much the self-cooking effect but it had a really small window of working dose vs toxic dose? So even if you didn't die of hyperthermia you'd die of it's various carcinogenic, mutagenic or other incompatibilities with cells?
Not really if you look into the literature. There were several studies done at Stanford and several hundred thousand people that took it for fat loss and less than 100 deaths from what I've seen. Also, a majority of those deaths were from suicide, which is both a sad thing and a terrible way to go. The deadly dose was about 5-6x the normal dose. There was a case of a girl ODing on it to get ready for spring break and I believe she was around 10x the standard dose. Note dosage is based off body weight.
Now there are other issues that can occur because of the MoA it causes you to burn through zinc and magnesium. There are thyroid issues that can occur, as well as the possibility of cataractics. Then there's the proton slip and electron leakage within the mitochondria. This is what causes a majority of the problems as it's a positive feedback loop for negative cascades. That can be almost entirely negated by keeping dose lower and doing your cardio. It can be done safely if you know what you're doing but most people aren't that reasonable.
Someone wrote an interesting book on it and took more of a conspiracy standpoint on it claiming it could be effective fat loss but because it was cheap and easy it would cut into big pharma making money. Can't say I agree with everything in the book but there was some useful information.
There's also a newer compound called BAM-15. In research it's more effective at fat loss and can be taken at much higher doses safely. I believe they got up to 20x the dnp standard dose without negative side effects in the lab rats.
coming at a time when temps are going up, permanently (well, for any human lifespan) people eating too much then burning calories to dump as waste heat completely tracks.
I take stims everyday and it's hell in summer
I've been wondering for a while if burned fat releases protein as if you had eaten the fat
Scientists have figured out a ton of things in a lab setting. But most of that is not something that scales up to the real world.
Okay, how do I get my hands on some of the stuff they used so I can inject it into my abdomen?
... exercise? :-P
Never!
Diet
As the other reply mentioned, "Never!" :-D
Oily rectal discharge anyone?
I like the mix of seriousness (serious scientific topic) and sensationalism (fat cells burning calories) in this article.
That sounds dangerous, the whole purpose of fat is to store energy if you’re smoking your own supply you won’t have anything left to sell.
This will certainly work 100% of the time, and with no awful consequences.
Remember that Alli pill a few years back that blocked fat absorption and gave everyone diarrhea?
No, but that's essentially what Wegovy/Ozempic does. I'm pretty sure diarrhea is necessary for weight loss (it's not).
One of your breasts will grow by 3 inches in diameter. The other gets a much larger and more sensitive second nipple towards the very top of your chest at the base of your neck completely visible regardless of how conservative you dress like.
The drug name is ofcourse, "Niplovyadalimumaboxidazeoicbenzoplastaze" it's fairly simple to draw.
Oh, it's fine, the brain is a different kind of fat! /s