Do spam calls "I wanna buy your house" ever work? Has anyone ever sold their house like that?

I'm in the unfortunate position to be job hunting, so I have to answer unknown numbers. For years, I've gotten "I'd like to buy your house" spam calls. I've never been in a situation where I'd sell to a random caller. I can't imagine one, either. I can imagine needing to sell my house, but I'd call a realtor or something. I wouldn't engage a random cold-caller.

Does that ever work? Is it legit? I assume it must be profitable, because they keep doing it.